The Sentosa SQ Melanoma Panel is a Next-Generation Sequencing-based test that simultaneously detects DNA sequence mutations in 10 genes from formalin-fixed paraffin-embedded (FFPE) samples for research use only. This panel is intended to be used on the Sentosa SX101 with the Sentosa SX FFPE II gDNA Kit in conjunction with the Sentosa ST401 and Sentosa SQ301 instruments.
For Research Use Only. Not for use in diagnostics procedures.
Target Genes | Number of Amplicons | Number of Target Mutations | Amplicon Locations in Exon(s) |
---|---|---|---|
BRAF | 1 | 37 | 15 |
NRAS | 2 | 27 | 2, 3 |
CDKN2A | 1 | 4 | 2 |
MAP2K1 | 1 | 4 | 3 |
FGFR3 | 3 | 9 | 7, 9, 14 |
AKT3 | 2 | 2 | 5, 6 |
KIT | 4 | 27 | 2, 11, 13, 17 |
PIK3CA | 1 | 15 | 11 |
GNAQ | 1 | 1 | 5 |
GNA11 | 1 | 1 | 5 |
System Control | 1 | NA | NA |
Total | 18 | 127 |
Supporting Research:
Providing Laboratory Efficiency and Effectiveness
Product | Pack Size | Item Number |
---|---|---|
Sentosa SQ 318 Chip Kit (8) RUO | 8 runs | 300301 |
Sentosa SQ Melanoma Reagents (4x8) RUO | 4x8 | 300221 |
Sentosa SQ Oncology Solutions (4x8) RUO | 4x8 | 300224 |
Sentosa SQ Sequencing Reagents (8) RUO | 8 | 300310 |
Sentosa SQ Sequencing Solutions (8) RUO | 8 | 300314 |
Sentosa SQ Sequencing Supplies (8) RUO | 8 | 300304 |
Sentosa ST Template Beads (8) RUO | 8 | 300320 |
Sentosa ST Template Reagents (8) RUO | 8 | 300317 |
Sentosa ST Template Solutions (8) RUO | 8 | 300323 |
Sentosa ST Template Supplies (8) RUO | 8 | 300326 |