Sentosa SQ Thyroid Cancer Panel
Detect sequence variants in thyroid cancer samples
The Sentosa SQ Thyroid Cancer Panel is a Next-Generation Sequencing (NGS)-based test that simultaneously detects hot spot mutations in 10 genes from formalin-fixed paraffin-embedded (FFPE) samples for research use only. This panel is intended to be used on the Sentosa SX101 with the Sentosa SX FFPE II gDNA Kit in conjunction with the Sentosa ST401 and Sentosa SQ301 instruments.
For Research Use Only. Not for use in diagnostics procedures.
| Target Genes | Number of Amplicons | Number of Target Mutations | Amplicon Locations in Exon(s) |
|---|---|---|---|
| BRAF | 2 | 15 | 11, 15 |
| CTNNB1 | 1 | 5 | 2 |
| EGFR | 4 | 10 | 18, 19, 20, 21 |
| FGFR3 | 3 | 9 | 7, 9, 14 |
| KRAS | 3 | 22 | 2, 3, 4 |
| NRAS | 3 | 19 | 2, 3, 4 |
| PTEN | 3 | 3 | 5, 7 |
| PIK3CA | 2 | 14 | 11, 22 |
| RET1 | 1 | 1 | 16 |
| TP53 | 3 | 7 | 4, 6, 7 |
| Total | 25 | 105 |
Provision of Reliable Results
- Minimal sample input - 10μm section of FFPE tissue or 5 ng DNA per library
- Automated and user-friendly data analysis and results reporting with Sentosa SQ Reporter
Providing Laboratory Efficiency
- From clinical sample to result in 2 days
- Detection of up to 5% variant frequency
- Seamless sample traceability and network connectivity with Sentosa Link
| Attribute | Value |
|---|---|
| Sample Input | 10 μm section of FFPE tissue (on glass slide or scroll) |
| Target Amplicons | 25 targets and 1 control |
| Target Mutations | 105 |
| Min. Coverage / Target Mutation | > 1,000 x |
| Analytical Sensitivity | ≥ 5 ng DNA input; 5% variant frequency for mutation detection |
| Product | Pack Size | Item Number |
|---|---|---|
| Sentosa SQ 318 Chip Kit (8) RUO | 8 runs | 300301 |
For availability in your country, please contact your Vela Diagnostics sales representative. Availability is subject to country's regulatory approval.
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Product Info |
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| 300301 Sentosa SQ 318 Chip Kit (8) (RUO) | V1.3 |  |
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