OncoKey SQ Hereditary Cancer Panel

Towards Precision Medicine in Healthcare

PURPOSE

OncoKey SQ Hereditary Cancer Panel

The OncoKey SQ Hereditary Cancer Panel (4x16) is a comprehensive next generation sequencing (NGS)-based assay designed to detect hotspot mutations (SNVs, indels) from 37 targeted genes frequently mutated in human cancers.

This panel is intended to be used on the Sentosa SX101 with Sentosa SX U-Prep Kit (4) for buccal swab, saliva swab, whole saliva and whole blood samples in conjunction with Sentosa SQ301 instruments.

* RUO: For research use only. Not for use in diagnostic procedures.

 

TARGET GENES

Biomarkers
APC CDKN2A MSH6 RAD51D TMEM127
ATM CHEK2 MUTYH RET TP53
BMPR1A EPCAM NBN SDHAF2 TSC1
BRCA1 FH NF1 SDHB TSC2
BRCA2 FLCN PALB2 SDHC VHL
BRIP1 MAX PMS2 SDHD  
CDH1 MLH1 PTEN SMAD4  
CDK4 MSH2 RAD51C STK11  

FEATURES AND BENEFITS

Supporting Clinical Research:

  • Pan-cancer test covering 37 frequently mutated genes
  • Detecting multiple targets in one run: SNVs and Indels
  • From clinical samples to result in 3 days

Providing Laboratory Efficiency:

  • Up to 15 samples (plus 1 system control)
  • Fully automated workflow from sample to result
  • Seamless sample traceability and IT connectivity
  • Automated comprehensive analysis and drug interpretation report

 

ONCOKEY AUTOMATED WORKFLOW

SPECIFICATIONS

Attribute OncoKey SQ Hereditary Cancer Panel
Regulatory Status RUO
Number of Genes 37 genes (868 amplicons)
DNA Input Requirement 2 ng/PCR reaction
Median Coverage 10x
Sample Throughput 16 samples
(including 1 system control)
Hands-on Time 2 hours
Turnaround Time 3 days
Limit of Detection 0.5 ng DNA Input/PCR reaction
Analytical Sensitivity 93.18%

PRODUCT FLYERS

ORDERING INFORMATION

ProductPack SizeItem Number
Sentosa SQ OncoKey Solutions (RUO) 4x16 300693
OncoKey SQ Hereditary Cancer Panel (4x16) (RUO) 4x16 690256
OncoKey SQ Hereditary Cancer Reagents (4x16) (RUO) 4x16 300834

For availability in your country, please contact your Vela Diagnostics sales representative. Availability is subject to country's regulatory approval.

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