OncoKey SQ Hereditary Cancer Panel
The OncoKey SQ Hereditary Cancer Panel (4x16) is a comprehensive next generation sequencing (NGS)-based assay designed to detect hotspot mutations (SNVs, indels) from 37 targeted genes frequently mutated in human cancers.
This panel is intended to be used on the Sentosa SX101 with Sentosa SX U-Prep Kit (4) for buccal swab, saliva swab, whole saliva and whole blood samples in conjunction with Sentosa SQ301 instruments.
* RUO: For research use only. Not for use in diagnostic procedures.
Biomarkers | ||||
APC | CDKN2A | MSH6 | RAD51D | TMEM127 |
ATM | CHEK2 | MUTYH | RET | TP53 |
BMPR1A | EPCAM | NBN | SDHAF2 | TSC1 |
BRCA1 | FH | NF1 | SDHB | TSC2 |
BRCA2 | FLCN | PALB2 | SDHC | VHL |
BRIP1 | MAX | PMS2 | SDHD | |
CDH1 | MLH1 | PTEN | SMAD4 | |
CDK4 | MSH2 | RAD51C | STK11 |
Supporting Clinical Research:
Providing Laboratory Efficiency:
Attribute | OncoKey SQ Hereditary Cancer Panel | |||
Regulatory Status | RUO | |||
Number of Genes | 37 genes (868 amplicons) | |||
DNA Input Requirement | 2 ng/PCR reaction | |||
Median Coverage | ≥10x | |||
Sample Throughput | 16 samples (including 1 system control) |
|||
Hands-on Time | 2 hours | |||
Turnaround Time | 3 days | |||
Limit of Detection | 0.5 ng DNA Input/PCR reaction | |||
Analytical Sensitivity | 93.18% |
OncoKey SQ Hereditary Cancer Panel Flyer | RUO | EN |
Product | Pack Size | Item Number |
---|---|---|
OncoKey SQ Hereditary Cancer Reagents (4x16) RUO | 4x16 | 300834 |
Sentosa SQ OncoKey Solutions (4x16) RUO | 4x16 | 300693 |
For availability in your country, please contact your Vela Diagnostics sales representative. Availability is subject to country's regulatory approval.
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