OncoKey SL 60 Plus Panel
Streamlining Precision Medicine for Cancer
OncoKey SL 60 Plus Panel on an Automated Workflow
The Oncokey SL 60 Plus Panel is a Next-Generation sequencing (NGS)-based Research Use Only (RUO) test intended for the detection of single nucleotide variations (SNVs), insertions/deletions (INDELs), copy number variations (CNVs), microsatellite instability (MSI), oncogenic pathogens and fusion genes in clinically relevant genes, in Formalin Fixed Paraffin Embedded (FFPE) Tissue specimens.
This test is automated on the Sentosa SX 101 with the OncoKey SX FFPE DNA/RNA Kit (4x16), OncoKey SL DNA Library Prep Kit (4x16), OncoKey SL RNA Library Prep Kit, Oncokey SL 60 Plus DNA/RNA Target Enrichment Kit, in conjunction with Illumina Miseq or NextSeq 500/550 systems.
OncoKey SL 60 Plus Panel on a Manual Workflow
The OncoKey SL 60 Plus Panel is also available as a manual solution.
This manual test is intended to be used with the OncoKey SX FFPE DNA/RNA Kit (4x16), OncoKey SL Manual DNA Library Prep Kit (96), OncoKey SL Manual RNA Library Prep Kit (96), OncoKey SL 60 Plus Manual DNA/RNA 8-Plex Target Enrichment Kit (24), in conjunction with Illumina Miseq or NextSeq 500/550 systems.
*RUO: For research use only. Not for use in diagnostic procedures.
Supporting Clinical Research:
- Focused pan-cancer test covering more than 60 clinically relevant genes
- Detects multiple cancer biomarkers in one run:
- SNVs, CNVs, INDELs, MSI, fusions, splice variants
- Oncogenic Viruses and Bacteria
- Optimal sensitivity, specificity, variant detection and sequencing coverage uniformity
- FFPE positive control, internal control and RNA housekeeping genes are included
- Local data storage to preserve patient data privacy
Providing Laboratory Efficiency:
- Up to 32 samples (Illumina Sequencing Platform dependent)
- Automated, sample-to-result workflow
- Generates results within 5 days, and less than 2.5 hours of hands-on time
- Manual option available for lower sample volumes
- Seamless sample traceability
- Automated comprehensive analysis and drug interpretation report by VELA Analytics
| Attribute | OncoKey SL 60 Plus Panel | |||
| Regulatory Status | RUO | |||
| Genomic Coverage | 266 kb (Human) 82.7 kb (Oncogenic Pathogens) |
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| Systems | MiSeq System, NextSeq 500/550 System | |||
| DNA Input Requirement | 40 ng DNA | |||
| RNA Input Requirement | 40 ng RNA | |||
| FFPE Input Requirement | Tumor content > 20%, 3 x 10 μm FFPE scrolls/slides | |||
| Median Coverage | > 200x | |||
| Sample Throughput | 8 samples per MiSeq run 32 samples per NextSeq 500/550 run |
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| Hands-on Time | ≤ 2.5 hours | |||
| Turnaround Time | 5 days from sample to result | |||
| Limit of Detection | 5% DNA VAF | |||
| Analytical Sensitivity | DNA: 100% RNA: 100% |
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| Analytical Specificity | DNA: 100% RNA: 100% |
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| OncoKey SL 60 Plus Panel | RUO | EN |
| Product | Pack Size | Item Number |
|---|---|---|
| OncoKey SL 60 Plus DNA 8-Plex Target Enrichment Reagents | 4x2 | 301031 |
| OncoKey SL 60 Plus DNA/RNA 8-Plex Target Enrichment Reagents (4x4) RUO | 4x4 | 301032 |
| OncoKey SL 60 Plus Manual DNA 8-Plex Target Enrichment Reagents | 24 | 301047 |
| OncoKey SL 60 Plus Manual DNA/RNA 8-Plex Target Enrichment Reagents | 24 | 301048 |
| OncoKey SL 60 Plus Manual RNA 8-Plex Target Enrichment Reagents | 24 | 301062 |
| OncoKey SL 60 Plus RNA 8-Plex Target Enrichment Reagents | 4x2 | 301065 |
| OncoKey SL 8-Plex Target Enrichment Solutions | 24 | 301053 |
| OncoKey SL 8-Plex Target Enrichment Solutions | 4x2 | 301037 |
| OncoKey SL 8-Plex Target Enrichment Solutions Kit (4x4) | 4x4 | 301038 |
| OncoKey SL DNA Library Prep Reagents | 4x16 | 301027 |
| OncoKey SL DNA Library Prep Solutions (4x16) | 4x16 | 301028 |
| OncoKey SL Internal Control Kit | 8x16 | 301024 |
| OncoKey SL Manual DNA Library Prep Adapters 1-32 | 96 | 301041 |
| OncoKey SL Manual DNA Library Prep Adapters 33-64 | 96 | 301042 |
| OncoKey SL Manual DNA Library Prep Reagents | 96 | 301039 |
| OncoKey SL Manual DNA Library Prep Solutions | 96 | 301040 |
| OncoKey SL Manual RNA Library Prep Adapters 65-96 | 96 | 301045 |
| OncoKey SL Manual RNA Library Prep Adapters 97-128 | 96 | 301046 |
| OncoKey SL Manual RNA Library Prep Reagents | 96 | 301043 |
| OncoKey SL Manual RNA Library Prep Solutions | 96 | 301044 |
| OncoKey SL Positive Control Kit (8) RUO | 8 | 301023 |
| OncoKey SL RNA Library Prep Reagent (4x16) | 4x16 | 301029 |
| OncoKey SL RNA Library Prep Solutions (4x16) | 4x16 | 301030 |
| Sentosa SQ Reporter Server for OncoKey SL Panels (T440) | 1 | 400254 |
| Sentosa SQ Reporter v2.5 | 480204 | |
| Sentosa SX FFPE DNA/RNA Kit Box 1 | 4x16 | 301025 |
| Sentosa SX FFPE DNA/RNA Kit Box 2 | 4x16 | 301026 |
| Sentosa SX Magnetic Plate | 400090 | |
| Sentosa SX NGS Starter Kit | 400105 | |
| Sentosa SX Thermoblock PCR 96 OC | 400088 | |
| VELA Analytics Report OncoKey SL Plus | 500260 | |
| VELA Analytics Server, T620 | 400102 | |
| VELA Analytics Software | 480175 | |
| VELA SL Wingman | 480182 |
For availability in your country, please contact your Vela Diagnostics sales representative. Availability is subject to country's regulatory approval.
For more product related documents, please contact us.
